?? ???? ??????? ?????? ?????????? ?? ????? ??????? ???????? ?? ?????? ????????? ??????? ?? ?????? ????? ??? ??????? ?????? ??????? ?? ??? ????? ?? ???? ????? ?? ??????? ??????.Respiratory depression can manifest at any time through opioid therapy, particularly when initiating and subsequent dosage will increase with OXYCONTIN. Consider this danger